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| Tobey Maguire | Sam Cahill |
| Jake Gyllenhaal | Tommy Cahill |
| Natalie Portman | Grace Cahill |
| Sam Shepard | Hank Cahill |
| Bailee Madison | Isabelle Cahill |
| Taylor Geare | Maggie Cahill |
| Patrick Flueger | Joe Willis |
| Clifton Collins Jr. | Maj. Cavazos |
| Carey Mulligan | Cassie Willis |
| Omid Abtahi | Yusuf |
| Ethan Suplee | Sweeney |
| Mare Winningham | Elsie Cahill |
| Josh Berry | Sgt. Freeman |
Siblings Sam and Tommy Cahill are as far apart as brothers can be; while Sam serves his country as a Marine, Tommy is a drifter who just got out of prison. When Sam is shot down and presumed dead in Afghanistan, Tommy vows to take care of Sam's wife, Grace, and his children. Tommy and Grace become close, and when Sam unexpectedly returns home, the consequences of their actions threaten the foundation of the entire family.
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